A longitudinal case series of IM ketamine for patients with severe and enduring eating disorders and comorbid treatment-resistant depression.

Terry SchwartzMary Ellen TrunkoDavid FeifelEmily LopezDanika PetersonGuido K W FrankWalter Kaye

Published in: Clinical case reports (2021)

Severe and enduring eating disorders (EDs) have the highest mortality rate of all psychiatric illnesses (Arch Gen Psychiatry, 2011, 68, 724), especially when comorbid with treatment-resistant depression (TRD) (Psychiatr Res, 2016, 244, 45). We report on four patients with enduring EDs and TRD treated with repeat ketamine over 12 + months, showing improvement in depression with only modest changes in ED symptoms.

Keyphrases

sleep quality
depressive symptoms
early onset
cardiovascular events
cardiovascular disease
type diabetes
chronic pain