Bone Marrow Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying circ_0050205 Attenuate Intervertebral Disc Degeneration.

Xiao-Jun YuQi-Kun LiuRui LuShan-Xi WangHao-Ran XuYing-Guang WangYuan BaoYong-Qiao JiangMeng-Wei LiHao Kang

Published in: Oxidative medicine and cellular longevity (2022)

In conclusion, BMSC-EVs promoted NPC survival-inhibited ECM degradation in NPCs and attenuated IDD progression via the circ_0050205/miR-665/GPX4 axis.

Keyphrases

bone marrow
mesenchymal stem cells
cell proliferation
long non coding rna
umbilical cord
long noncoding rna
extracellular matrix
cell therapy