Humoral immunity response to human endogenous retroviruses K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases.
G ArruG MameliG A DeianaA L RassuR PireddaE SechiE CaggiuM BoE NakoDaniele UrsoSara MariottoS FerrariG ZanussoS MonacoG SechiLeonardo Antonio SechiPublished in: European journal of neurology (2018)
Increased circulating levels of Abs directed against the HERV-W env-su93-108 and HERV-W env-su248-262 peptide fragments could serve as possible biomarkers in patients with MS. Similarly, increased circulating levels of Abs directed against the HERV-K env-su19-37 peptide fragment could serve as a possible early novel biomarker in patients with ALS.