In RRP, serologic response to HPV is frequently absent and slow to develop.
Farrel J BuchinskyNicole RuszkayWilliam L ValentinoCraig S DerkayJohn E McClayRobert W BastianCharles M MyerKevin W LollarDalya GurisPublished in: PloS one (2020)
People with RRP are capable of developing a humoral response to HPV6 and HPV11. That response appears to be robust when initiated by the HPV vaccine, but either nonexistent or slow to develop in response to infection. Most in remission do not have demonstrable antibody levels against HPV6 or HPV11.