Intratumoral Electroporation of Plasmid Encoded IL12 and Membrane-Anchored Anti-CD3 Increases Systemic Tumor Immunity.

Mia Han Bianca Nguyen Jack Y LeeErica BrowningJun ZhangAnandaroop MukhopadhyayRavindra GujarJon SalazarReneta HermizLauren SvensonAnnah S Rolig William L Redmond Alain Patrick Algazi Adil I Daud David A CantonChristopher G Twitty

Published in: Molecular cancer research : MCR (2022)

This DNA-encodable polyclonal T-cell stimulator (membrane-anchored anti-CD3 plasmid) may represent a key addition to intratumoral IL12 therapies in the clinic.

Keyphrases

escherichia coli
crispr cas
primary care
nk cells
single molecule