A measure of agreement across numerous conditions: assessing when changes in network structures are tissue-specific.

Published in: BMC genomics (2019)

Our results offer novel substantial evidence that changes in network structure across tissues can be inferred independently of samples, algorithms and experiments (RNA-sequencing or microarrays). Reliability measures, such as λ, can inform on the tissues where changes in a network's structure are likely functional. An R package is available at https://github.com/isglobal-brge/lambda .

Keyphrases

gene expression
machine learning
high resolution
deep learning
network analysis
mass spectrometry