Preparation of Fluorescent Carbon Dots Composites and Their Potential Applications in Biomedicine and Drug Delivery-A Review.
Yaru ChaiYashan FengKun ZhangJing'an LiPublished in: Pharmaceutics (2022)
Carbon dots (CDs), a new member of carbon nanostructures, rely on surface modification and functionalization for their good fluorescence phosphorescence and excellent physical and chemical properties, including small size (<10 nm), high chemical stability, biocompatibility, non-toxicity, low cost, and easy synthesis. In the field of medical research on cancer (IARC), CDs, a new material with unique optical properties as a photosensitizer, are being applied to heating local apoptosis induction of cancer cells. In addition, imaging tools can also be combined with a drug to form the nanometer complex compound, the imaging guidance for multi-function dosage, so as to improve the efficiency of drug delivery, which also plays a big role in genetic diagnosis. This paper mainly includes three parts: The first part briefly introduces the synthesis and preparation of carbon dots, and summarizes the advantages and disadvantages of different preparation methods; The second part introduces the preparation methods of carbon dot composites. Finally, the application status of carbon dot composites in biomedicine, cancer theranostics, drug delivery, electrochemistry, and photocatalysis is summarized.
Keyphrases
- drug delivery
- visible light
- quantum dots
- low cost
- papillary thyroid
- molecularly imprinted
- cancer therapy
- high resolution
- photodynamic therapy
- reduced graphene oxide
- oxidative stress
- squamous cell
- energy transfer
- healthcare
- drug release
- physical activity
- cell death
- squamous cell carcinoma
- emergency department
- genome wide
- lymph node metastasis
- mental health
- endoplasmic reticulum stress
- big data
- single molecule
- fluorescence imaging
- aqueous solution
- cell cycle arrest
- drug induced
- cell proliferation
- pi k akt
- artificial intelligence