Cystic fibrosis carriership and tuberculosis: hints toward an evolutionary selective advantage based on data from the Brazilian territory.

Lander BoschBarbara BoschKris De BoeckTim NawrotIsabelle MeytsDominique VannesteCleonice Alexandre Le BourlegatJulio CrodaLuiz Vicente Ribeiro Ferreira da Silva Filho

Published in: BMC infectious diseases (2017)

We provide exploratory support for the hypothesis that carrying a single CFTR mutation arms against Mtb infections.

Keyphrases

cystic fibrosis
mycobacterium tuberculosis
pulmonary tuberculosis
pseudomonas aeruginosa
lung function
electronic health record
genome wide
big data
hiv aids
data analysis
machine learning
dna methylation
deep learning
hepatitis c virus
human immunodeficiency virus