Prevention of Postoperative Cognitive Dysfunction by Minocycline in Elderly Patients after Total Knee Arthroplasty: A Randomized Double-blind Placebo-controlled Clinical Trial.

Tomonori TakazawaTatsuo HoriuchiMasaki OriharaKazuhiro NagumoAkihiro TomiokaYuki IdenoKunihiko HayashiHideaki YashimaTakuya ArakiKazuhisa HatayamaMasanori TerauchiYoshio IkedaShigeru Saito

Published in: Anesthesiology (2022)

Keyphrases

double blind
placebo controlled
clinical trial
phase ii
phase iii
patients undergoing
study protocol
pain management
phase ii study
open label
rectal cancer
chronic pain
locally advanced