Coronavirus Disease 2019 Vaccine Impact on Rates of Severe Acute Respiratory Syndrome Coronavirus 2 Cases and Postvaccination Strain Sequences Among Health Care Workers at an Urban Academic Medical Center: A Prospective Cohort Study.
Tara C BoutonSara LodiJacquelyn TurcinovicBeau SchaefferSarah E WeberEmily QuinnCathy KornJacqueline SteinerElissa M Schechter-PerkinsElizabeth DuffyElizabeth J RaganBradford P TaylorNancy MillerRavin DavidoffWilliam P HanageJohn ConnorCassandra PierreKaren R JacobsonPublished in: Open forum infectious diseases (2021)
Our results indicate an early positive impact of vaccines on SARS-CoV-2 case rates. Post-vaccination isolates did not show unusual genetic diversity or selection for mutations of concern.