Pd-Catalyzed Arylperfluoroalkylation of Unactivated Olefins for the Synthesis of Heterocycles.

An efficient and highly practical palladium-catalyzed arylperfluoroalkylation of unactivated olefins is presented here. A variety of perfluoroalkylated heterocyclic derivatives can be obtained in high regioselectivity. The reaction proceeds mildly without the electronic activation of the aryl group and features high generality, low-cost fluoroalkylated sources and good functional-group compatibility.