Hyperinsulinemic-euglycaemic clamp strengthens the insulin resistance in nonclassical congenital adrenal hyperplasia.

Ariane Delai Patricia Moreira Gomes Maria Cristina Foss de FreitasJorge EliasSonir Roberto Rauber Antonini Margaret de Castro Ayrton Custodio Moreira Livia M Mermejo

Published in: The Journal of clinical endocrinology and metabolism (2021)

Using the gold standard method, the hyperinsulinemic-euglycemic clamp, insulin resistance was present in NC-CAH patients and related to prolonged use and long-acting glucocorticoid treatment. Glucocorticoid replacement and cardiometabolic risks should be monitored regularly in NC-CAH.

Keyphrases

insulin resistance
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
type diabetes
prognostic factors
metabolic syndrome
adipose tissue
high fat diet
patient reported outcomes
polycystic ovary syndrome
risk assessment
climate change