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A novel HLA-A allele, HLA-A*02:544.

X ZhuT YangR TanP SuZ LuoX Zhen
Published in: Tissue antigens (2016)
The novel allele HLA-A*02:544 has two nucleotide changes from its most closely related allele, HLA-A*02:148. Firstly at nucleotide 255 where C → T (codon 60 GAC → GAT), resulting in a non-coding change as GAC and GAT both code for the same amino acid aspartic acid. Secondly at nucleotide 368 where T → G (codon 98 TTT → TGT) resulting in a coding change, 98 phenylalanine is changed to cysteine.
Keyphrases
  • amino acid