Lipopolysaccharide-binding protein is a distinctive biomarker of abnormal pain threshold in the general Japanese population.

Kazuhiro KudohHiroki MizukamiChieko ItabashiNobuo FukeSho OsonoiYuki TakeuchiKanichiro WadaAkiko IgawaSaori OgasawaraYasuyuki IshibashiKenichi HakamadaSoroku YagihashiShigeyuki Nakaji

Published in: BMJ open diabetes research & care (2021)

Individuals with high LBP exhibited an elevated PINT in the Japanese population. Low level of inflammation evoked by metabolic endotoxemia is possibly implicated in the pathophysiology of SFN from pre-diabetic stage.

Keyphrases

binding protein
lps induced
oxidative stress
type diabetes
inflammatory response
pain management
neuropathic pain
spinal cord injury
spinal cord