Whole-body distribution of tenofovir, emtricitabine and dolutegravir in non-human primates.
Thibaut GeléHélène GougetNastasia DimantValérie FurlanJon CollinsErin M B ScholzChris M ParryRoger Le GrandOlivier LambotteDelphine DesjardinsAurélie Barrail-TranPublished in: The Journal of antimicrobial chemotherapy (2024)
Overall, this study determines the first whole-body distribution in a validated NHP model. These data have important implications for future preclinical and clinical studies for the development of novel HIV therapies towards an HIV cure.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv infected patients
- hiv aids
- hiv testing
- endothelial cells
- hepatitis c virus
- men who have sex with men
- electronic health record
- current status
- induced pluripotent stem cells
- stem cells
- cell therapy
- machine learning
- mesenchymal stem cells
- artificial intelligence
- data analysis