The association between cigarette smoking and efavirenz plasma concentration using the population pharmacokinetic approach.

Ngah Kuan ChowSabariah Noor HarunE-Jinq WongLee Lee LowSiti Maisharah Sheikh GhadziAmer Hayat Khan

Published in: British journal of clinical pharmacology (2021)

HIV-positive smokers presented with significantly higher efavirenz clearance and unfavourable clinical outcomes. Close monitoring of adherence and clinical response among smokers is warranted.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
smoking cessation
human immunodeficiency virus
hiv infected patients
men who have sex with men
south africa
type diabetes
metabolic syndrome