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The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom.

Matthew HickmanColin SteerKate TillingAaron G LimJohn MarsdenTim MillarSir John StrangMaggie TelferPeter VickermanJohn Macleod
Published in: Addiction (Abingdon, England) (2018)
In UK general medical practice, opioid substitution treatment with buprenorphine is associated with a lower risk of all-cause and drug-related poisoning mortality than methadone. In the population, buprenorphine is unlikely to give greater overall protection because of the relatively shorter duration of treatment.
Keyphrases
  • primary care
  • healthcare
  • cardiovascular events
  • chronic pain
  • risk factors
  • type diabetes
  • cardiovascular disease
  • pain management
  • coronary artery disease
  • replacement therapy
  • adverse drug