Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans.
Léa ChuzelSamantha L FossaMadison L BoisvertSamanta CajicRené HennigMehul B GanatraUdo ReichlErdmann RappChristopher H TaronPublished in: Microbial cell factories (2021)
The present study demonstrates the feasibility of using functional metagenomic screening combined with glycoanalytics to discover enzymes that act upon chemical modifications of glycans. The discovered enzymes represent new specificities that can help resolve the presence of GlcNAc-6-SO4 in N-glycan structural analyses.
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