Fecal sphingolipids predict parenteral nutrition-associated cholestasis in the neonatal intensive care unit.

Thomas J MoutinhoDeborah A PowersGabriel F HansonShira LevyRajiv BavejaIsabel HefnerMasouma MohamedAlaa AbdelghaniRobin L BakerJason A PapinRachelle Prantil-BaunSuchitra K Hourigan

Published in: JPEN. Journal of parenteral and enteral nutrition (2022)

We demonstrate the potential for stool metabolomics to enhance early identification of PNAC risk. Earlier detection of high-risk infants would empower proactive mitigation with alterations to PN for at-risk infants and optimization of energy nutrition with PN for infants at lower risk.

Keyphrases

climate change
physical activity
mass spectrometry
human health
loop mediated isothermal amplification