Tetrandrine ameliorates cognitive deficits and mitigates tau aggregation in cell and animal models of tauopathies.

Benjamin Chun-Kit TongAlexis Shiying HuangAston Jiaxi WuAshok IyaswamyOlivia Ka-Yi HoAnna Hau-Yee KongSravan Gopalkrishnashetty SreenivasmurthyZhou ZhuChengfu SuJia LiuJuxian SongMin LiKing-Ho Cheung

Published in: Journal of biomedical science (2022)

homeostasis, thereby restoring ALP function, could be an effective general strategy for the development of novel therapies for tauopathies.

Keyphrases

single cell
cell therapy
mouse model
cerebrospinal fluid
stem cells
radiation induced
radiation therapy
mesenchymal stem cells