Impact of residual disease biomarkers on the prognosis of HER2-positive breast cancer following neoadjuvant therapy.

Youzhao MaMingda ZhuMinhao LvPeng YuanXiuchun ChenZhenzhen Liu

Published in: Cancer medicine (2023)

ER, PR, HER2, and Ki-67 changed significantly after NAT, but no impact of these changes on DFS was observed in this study. Postoperative N stage, postoperative ER status, MP grade, and targeted therapy were independent prognostic factors in patients with HER2-positive breast cancer after NAT.

Keyphrases

positive breast cancer
prognostic factors
patients undergoing
estrogen receptor
endoplasmic reticulum
rectal cancer
lymph node
locally advanced
neoadjuvant chemotherapy
radiation therapy
replacement therapy