Amphiphilic amidines as potential plasmic membrane-targeting antifungal agents: synthesis, bio-activities and QSAR.

Guangyou ChenJing BaiXinyan WuXinyi HuoYong-Qiang Li Peng Lei Zhi-Qing Ma

Published in: Pest management science (2024)

Amphiphilic amidines can acquire antifungal activities by acting on the plasmic membrane. Compound 5g could be a promising lead in discovering novel fungicidal candidates. © 2024 Society of Chemical Industry.

Keyphrases

candida albicans
molecular docking
molecular dynamics
cancer therapy
human health
risk assessment
climate change