Monitoring of Tobramycin Exposure: What is the Best Estimation Method and Sampling Time for Clinical Practice?

Yanhua GaoStefanie Hennig Michael A Barras

Published in: Clinical pharmacokinetics (2020)

Sampling times markedly influence bias in AUC0-24 estimation, leading to greatly varied dose adjustments. The impact of blood sampling times on dosing decisions is reduced when using Bayesian forecasting.

Keyphrases

clinical practice