The role of oxidant stress and gender in the erythrocyte arginine metabolism and ammonia management in patients with type 2 diabetes.

Martha L Contreras-ZentellaLourdes Sánchez-SevillaJuan A Suárez-CuencaMarisela Olguín-MartínezMartha G Alatriste-ContrerasNorberto García-GarcíaLorena OrozcoRolando Hernández-Muñoz

Published in: PloS one (2019)

We found evidence of a putative role of RBC as an extra-hepatic mechanism for controlling serum levels of nitrogen-related metabolites, which differs according to gender in healthy subjects. Type 2 DM promotes higher ammonia, citrulline, and MDA blood levels, which culminate in a loss of the differential management of nitrogen-related metabolites seen in healthy women and men.

Keyphrases

ms ms
mental health
room temperature
polycystic ovary syndrome
anaerobic digestion
metabolic syndrome
pregnant women
cell proliferation
cell death
middle aged
stress induced
cervical cancer screening