The fast block to polyspermy breaks with convention.

Published in: The Journal of general physiology (2023)

JGP study (Komondor et al. 2023. J. Gen. Physiol. https://doi.org/10.1085/jgp.202213258) reveals that conventional PLC activation pathways are not required for the fertilization-induced depolarization of Xenopus eggs that prevents the entry of additional sperm.

Keyphrases

high glucose
diabetic rats
mouse model
drug induced
cell free
oxidative stress