Characterization and genome-informatic analysis of a novel lytic mendocina phage vB_PmeS_STP12 suitable for phage therapy pseudomonas or biocontrol.
Sani Sharif UsmanEvangeline ChristinaPublished in: Molecular biology reports (2024)
Taken together, characterization, morphological analysis and genome-informatics indicated that vB_PmeS_STP12 is podovirus morphotype belonging to the class Caudoviticetes, family Zobellviridae which appeared to be devoid of integrase gene, ARGs, CRISPR arrays, virulence factors and toxins genes, exhibiting stability and infectivity at wide range of pH (4 to10) and temperature (-20 to 70 °C), thereby making vB_PmeS_STP12 suitable for phage therapy or biocontrol. Based on the bibliometric analysis and data availability with respect to sequences deposited in GenBank, this is the first report of a phage infecting Pseudomonas mendocina.
Keyphrases
- pseudomonas aeruginosa
- genome wide
- biofilm formation
- escherichia coli
- staphylococcus aureus
- cystic fibrosis
- big data
- dna methylation
- electronic health record
- stem cells
- copy number
- gene expression
- bone marrow
- mesenchymal stem cells
- antibiotic resistance genes
- artificial intelligence
- microbial community
- deep learning
- genome wide analysis
- anaerobic digestion