Exosomes Play an Important Role in the Progression of Plasma Cell Mastitis via the PI3K-Akt-mTOR Signaling Pathway.

Xiaohong WangYong HanJian LiuYingzhe ZhangKai ChengJiwei GuoQingqun GuoSong LiuHongguang SunYitong HuaGuoqiang ZhangShujian XuFengli GuoZhenlin Yang

Published in: Mediators of inflammation (2019)

Our results revealed the role of exosomes acting as critical signal introduction facilitators in the progression of plasma cell mastitis and identified potential key genes in the regulation of this process. These results will help to dissect the molecular mechanism of PCM and provide therapeutic targets.

Keyphrases

single cell
signaling pathway
mesenchymal stem cells
stem cells
cell therapy
pi k akt
epithelial mesenchymal transition
cell proliferation
climate change
human health
transcription factor
genome wide identification