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Growth Hormone Mediates Its Protective Effect in Hepatic Apoptosis through Hnf6.

Kewei WangMinhua WangMaureen GannonAi Xuan Le Holterman
Published in: PloS one (2016)
GH broad protective actions on hepatocytes during liver injury are effected through Hnf6, with Hnf6 transcriptional activation of Ciap1 as an underlying molecular mediator.
Keyphrases
  • liver injury
  • growth hormone
  • drug induced
  • nuclear factor
  • oxidative stress
  • gene expression
  • endoplasmic reticulum stress
  • cell death
  • cell cycle arrest
  • transcription factor
  • toll like receptor