The effect of higher versus lower protein delivery in critically ill patients: a systematic review and meta-analysis of randomized controlled trials.
Zheng-Yii LeeCindy Sing Ling YapM Shahnaz HasanJulia Patrick EngkasanBarakatun-Nisak Mohd YusofAndrew G DayJayshil J PatelDaren K HeylandPublished in: Critical care (London, England) (2021)
In critically ill patients, a higher daily protein delivery was not associated with any improvement in clinical or patient-centered outcomes. Larger, and more definitive RCTs are needed to confirm the effect of muscle loss attenuation associated with higher protein delivery. PROSPERO registration number: CRD42021237530.