Visualization-assisted binning of metagenome assemblies reveals potential new pathogenic profiles in idiopathic travelers' diarrhea.
Qiyun ZhuChristopher L DupontMarcus B JonesKevin M PhamZhi-Dong JiangHerbert L DuPontSarah K HighlanderPublished in: Microbiome (2018)
Our study highlights the strength of assembly-based metagenomics, especially the manually curated, visualization-assisted binning of contigs, in resolving unusual and under-characterized pathogenic profiles of human-associated microbiomes. Results show that TD may be polymicrobial, with multiple novel cellular and viral strains as potential players in the diarrheal disease.