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Titres and neutralising capacity of SARS-CoV-2-specific antibodies in human milk: a systematic review.

Jia Ming LowYue Wey LowYoujia ZhongCheuk Yiu Charlotte LeeMing ChanNicholas Beng Hui NgZubair AminYvonne Peng Mei Ng
Published in: Archives of disease in childhood. Fetal and neonatal edition (2021)
Human milk of lactating individuals after COVID-19 infection contains anti-SARS-CoV-2-specific IgG, IgM and/or IgA, even after mild or asymptomatic infection. Current evidence demonstrates that these antibodies can neutralise SARS-CoV-2 virus in vitro. Holder pasteurisation deactivates SARS-CoV-2-specific IgA, while high-pressure pasteurisation preserves the SARS-CoV-2-specific IgA function.
Keyphrases
  • sars cov
  • human milk
  • respiratory syndrome coronavirus
  • low birth weight
  • heat stress