Chlamydia pneumoniae-Induced IFN-Gamma Responses in Peripheral Blood Mononuclear Cells Increase Numbers of CD4+ but Not CD8+ T Effector Memory Cells.

Tamar Anne Smith-NorowitzSarah ShididYitzchok M NorowitzStephan Kohlhoff

Published in: Journal of blood medicine (2021)

C. pneumoniae-induced PBMC IFN-gamma+ responses increased numbers of CD4+ IL-2+ and CD4+IL-4+ TEM cells, while CD8+IL-2+ and CD8+IL-4+ TEMs decreased. Production of IFN-gamma by C. pneumoniae infected PBMC should be further studied as a biomarker of persistent infection in humans.

Keyphrases

dendritic cells
induced apoptosis
nk cells
immune response
high glucose
oxidative stress
working memory
endothelial cells