Heme oxygenase-1 prevents non-alcoholic steatohepatitis through modulating mitochondrial quality control.

Dongdong LiXiwei YuanShiming DongZaid Al-DhaminJinghua DuNa Fu Yue-Min Nan

Published in: Acta physiologica (Oxford, England) (2023)

HO-1 attenuates diet-induced steatohepatitis by preventing mitochondrial dysfunction, indicating that HO-1 may constitute a potential therapeutic target for NASH.

Keyphrases

quality control
pi k akt
oxidative stress
signaling pathway
liver injury
liver fibrosis
mouse model
human health
cell proliferation
drug induced
risk assessment