Restoration of a healthy intestinal microbiota normalizes portal hypertension in a rat model of nonalcoholic steatohepatitis.

Teresa García-LezanaImma RaurellMiren BravoManuel Torres-ArauzMaría Teresa SalcedoAlba SantiagoAndreu SchoenenbergerChaysavanh ManichanhJoan GenescàMaría MartellSalvador Augustin

Published in: Hepatology (Baltimore, Md.) (2018)

The IM exerts a direct influence in the development of PH in rats with diet-induced NASH and dysbiosis; PH, insulin resistance, and endothelial dysfunction revert when a healthy IM is restored. (Hepatology 2018;67:1485-1498).

Keyphrases

insulin resistance
blood pressure
adipose tissue
type diabetes
metabolic syndrome
polycystic ovary syndrome
skeletal muscle
glycemic control