Wheezing preschool children with early-onset asthma reveal a specific metabolomic profile.

Silvia CarraroSara BozzettoGiuseppe GiordanoDania El MazloumMatteo StoccheroPaola PirilloStefania ZanconatoEugenio Baraldi

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2018)

Metabolomic urinary profile can discriminate preschoolers with recurrent wheezing who will outgrow their symptoms from those who have early-onset asthma. These results may pave the way to the characterization of early non-invasive biomarkers capable of predicting asthma development.

Keyphrases

early onset
late onset
chronic obstructive pulmonary disease
lung function
allergic rhinitis
cystic fibrosis
genome wide
gene expression
dna methylation