Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters.

Luiz Gustavo Teixeira AlvesMorris BaumgardtChristine LangnerMara FischerJulia Maria AdlerJudith BusheTheresa Catharina FirschingGuido MastrobuoniJenny GrobeKatja HoenzkeStefan KempaAchim Dieter GruberAndreas Christian HockeJakob TrimpertEmanuel WylerMarkus Landthaler

Published in: BMJ open respiratory research (2024)

Altogether, we show that HSP90 inhibition could serve as a potential treatment option for moderate and severe cases of COVID-19.

Keyphrases

sars cov
heat shock protein
heat shock
heat stress
respiratory syndrome coronavirus
coronavirus disease
high intensity
early onset
combination therapy
oxidative stress
climate change