Dopamine D1 and D2 receptors mediate analgesic and hypnotic effects of l-tetrahydropalmatine in a mouse neuropathic pain model.

Yuan-Yuan LiuTian-Xiao WangJi-Chuan ZhouWei-Min QuZhi-Li Huang

Published in: Psychopharmacology (2019)

These findings indicated that l-THP exerted analgesic effects by agonism D1R and antagonism D2R, and the antagonism of D2R mediated the hypnotic effect of l-THP in PSNL mice.

Keyphrases

neuropathic pain
spinal cord
spinal cord injury
high fat diet induced
type diabetes
skeletal muscle
adipose tissue
anti inflammatory