Sulfatide inhibits fibroblast growth, activation and oxidative stress induced by ectopic insulin.

Allan Roeske-NielsenJan-Eric MånssonHasim TekinKlaus RieneckKlaus BendtzenKarsten Buschard

Published in: Diabetes, obesity & metabolism (2023)

Sulfatide strongly inhibits fibroblast growth. We therefore suggest the addition of sulfatide to injectable commercial insulin formulations, which would reduce adverse fibroblast growth and improve well-being in patients with diabetes.

Keyphrases

type diabetes
oxidative stress
dna damage
glycemic control
signaling pathway
adipose tissue
electronic health record
heat stress
hyaluronic acid
skeletal muscle