Pericardial malignant solitary fibrous tumour with right atrial invasion - a case report and literature review.
Li-Ping ZhangLu ZhangGuanqun WangBinay Kumar AdhikariQuan LiuWei-Hua ZhangPublished in: The Journal of international medical research (2019)
Solitary fibrous tumours are unusual neoplasms that develop from mesenchymal cells, usually originating from the pleura. A pericardial solitary fibrous tumour is an extremely rare occurrence. We report a 64-year-old woman who presented to the hospital with chief complaints of dyspnoea and abdominal distension. Echocardiography and enhanced computed tomography revealed an intrapericardial tumour with local invasion to the right atrium. Histopathological examination of a biopsy specimen showed a patternless distribution of spindle-shaped cells in a collagen stroma, with a high mitosis rate. Immunohistochemistry was positive for vimentin, CD34, and Bcl-2. The final diagnosis was a pericardial malignant solitary fibrous tumour with right atrial invasion. Surgical resection of the tumour was not performed because of its invasion into the myocardium. We systematically reviewed the literature on cardiac solitary fibrous tumours up to 2019.
Keyphrases
- catheter ablation
- atrial fibrillation
- left atrial
- cell migration
- computed tomography
- induced apoptosis
- cell cycle arrest
- left ventricular
- rare case
- stem cells
- magnetic resonance imaging
- pulmonary hypertension
- emergency department
- magnetic resonance
- oxidative stress
- pulmonary arterial hypertension
- ultrasound guided
- inferior vena cava
- fine needle aspiration