Diagnostic and prognostic value of 18F-FDG PET, CT, and MRI in perineural spread of head and neck malignancies.
Laurent DercleDana HartlLaura Rozenblum-BeddokFatima-Zohra MokraneRomain-David SebanRandy YehFrançois BidaultSamy AmmariPublished in: European radiology (2017)
• 18F-FDG PET/CT detects PNS in FDG-avid HNM. • PNS metabolism is more heterogeneous than healthy tissue. • PNS diagnosis is crucial: most patients were asymptomatic, N0 and M0. • PNS diagnosis is associated with poorer overall survival in SCC. • PET/CT- or PET/MRI-guided management strategies should be evaluated.