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Determining the Degree of Dopaminergic Denervation Based on the Loss of Nigral Hyperintensity on SMWI in Parkinsonism.

Yun Jung BaeYoo Sung SongJong Min KimByung Se ChoiYoonho NamJi-Hyun ChoiWon Woo LeeJae Hyoung Kim
Published in: AJNR. American journal of neuroradiology (2021)
Nigral hyperintensity on SMWI showed high positive predictive value and low negative predictive value with dopaminergic degeneration on 123I-FP-CIT SPECT. In patients with Parkinson disease, the loss of nigral hyperintensity is prominent in patients with lower striatal specific binding ratios.
Keyphrases
  • parkinson disease
  • deep brain stimulation
  • dna binding
  • transcription factor
  • functional connectivity
  • drug induced