Defining extended half-life rFVIII-A critical review of the evidence.
Johnny N MahlanguGuy Aaron YoungCedric HermansV BlanchetteE BerntorpE SantagostinoPublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2018)
In this systematic review, a pragmatic definition of EHL rFVIII has been proposed that should provide better clarity in clinical discussions surrounding the appropriate use of rFVIII products. At present, only products using PEGylation or Fc fusion half-life extension technology meet the proposed criteria for definition of EHL rFVIII.
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