Platelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia-an exploratory study.
Tove LekvaArvind Y Fm SundaramMarie Cecilie Paasche RolandJune ÅsheimAnnika E MichelsenErrol R NorwitzPål AukrustGregor D GilfillanThor UelandPublished in: BMC medicine (2023)
Platelet-derived and mitochondrial RNA were highly expressed in plasma EVs and were decreased in EVs isolated from women with PE compared to without PE. LncRNAs were mostly increased in PE. The MT-TA in leukocytes may be a useful biomarker for prediction and/or early detection of PE.