Anatomical Site, Viral Ribonucleic Acid Abundance, and Time of Sampling Correlate With Molecular Detection of Severe Acute Respiratory Syndrome Coronavirus 2 During Infection.

F Julian LantryNusrat J EpsiSimon D PollettMark P SimonsDavid A LindholmRhonda E ColomboAnthony C FriesRyan C MavesAnuradha GanesanGregory C UtzTahaniyat LalaniAlfred G SmithRupal M ModyChristopher J ColomboSharon W ChiCristian MadarNikhil HuprikarDerek T LarsonSamantha BazanChristopher C BroderEric D LaingCaroline EnglishCharlotte LanteriKatrin MendeDavid R TribbleBrian K AganTimothy H BurgessStephanie A Richardnull null

Published in: Open forum infectious diseases (2021)

NP swabs detected more SARS-CoV-2 cases than non-NP swabs, and the sensitivity of the non-NP swabs decreased with time postsymptom onset. While other swabs may be simpler to collect, NP swabs present the best chance of detecting SARS-CoV-2 RNA, which is essential for clinical care as well as genomic surveillance.

Keyphrases

sars cov
respiratory syndrome coronavirus
healthcare
coronavirus disease
public health
palliative care
quality improvement
copy number
affordable care act