Characterization of lignans in Forsythiae Fructus and their metabolites in rats by ultra-performance liquid chromatography coupled time-of-flight mass spectrometry.
Feng-Xiang ZhangZi-Ting LiChang LiMin LiZhi-Hong YaoXin-Sheng YaoYi DaiPublished in: The Journal of pharmacy and pharmacology (2020)
This work revealed the in-vivo metabolism of FF, and reported the characteristic metabolic reactions of lignans for the first time. It was also provided the foundation for the further investigation on pharmacodynamic components of FF or TCMs containing FF.