LAMC1 is a prognostic factor and a potential therapeutic target in endometrial cancer.

Haruko Kunitomi Yusuke Kobayashi Ren-Chin Wu Takashi Takeda Eiichiro Tominaga Kouji Banno Daisuke Aoki

Published in: Journal of gynecologic oncology (2019)

LAMC1 overexpression is a potent biomarker for identifying endometrial cancer patients needing aggressive adjuvant therapy. We elucidated 8 candidate genes that may mediate progression of LAMC1 overexpressing cancer. Further investigation of the underlying mechanism should lead to the discovery of new therapeutic targets.

Keyphrases

endometrial cancer
prognostic factors
papillary thyroid
small molecule
squamous cell
cell proliferation
high throughput
transcription factor
lymph node metastasis
anti inflammatory
human health
risk assessment
childhood cancer