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Alexithymia and anhedonia in early Richardson's syndrome and progressive supranuclear palsy with predominant parkinsonism.

Francesca AssognaClelia PellicanoLuca CravelloCinzia SaviniLucia MacchiusiMariangela PierantozziAlessandro StefaniBruno MercuriCarlo CaltagironeFrancesco E PontieriGianfranco Spalletta
Published in: Brain and behavior (2019)
Alexithymia is identifiable very early in PSP-P and PSP-RS patients. Alexithymic symptoms differentiate PSP-RS group from PD group but not between the two subtypes of PSP. Further, alexithymia in PSP seems to be predicted by the presence of depression. Altered emotional capability could be related to specific neurophysiological dysfunction occurring precociously in PSP; therefore, its identification could orient the diagnosis toward PSP cases.
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