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Erbb4 Deletion From Inhibitory Interneurons Causes Psychosis-Relevant Neuroimaging Phenotypes.

Amanda KiemesMaria Elisa Serrano NavacerradaEugene KimKaren RandallCamilla SimmonsLoreto Rojo GonzalezMarija-Magdalena PetrinovicDavid J LythgoeDiana RotaruDavide Di CensoLydiane HirschlerEmmanuel L BarbierAnthony C VernonJames M StoneCathy DaviesDiana CashGemma Modinos
Published in: Schizophrenia bulletin (2022)
These findings demonstrate that specific disruption of cortical inhibitory interneurons in mice recapitulate some of the key neuroimaging findings in patients with psychosis, and link inhibitory interneuron deficits to non-invasive measures of brain function and neurochemistry that can be used across species.
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