Expression of immune checkpoint molecules programmed death protein 1, programmed death-ligand 1 and inducible T-cell co-stimulator in mycosis fungoides and Sézary syndrome: association with disease stage and clinical outcome.
Cosimo Di RaimondoBelen Rubio-GonzalezJoycelynne PalmerDennis D WeisenburgerJasmine ZainXiwei WuZhen HanSteven T RosenJoo Y SongChristiane QuerfeldPublished in: The British journal of dermatology (2022)
These findings demonstrate the existence of a complex immunoregulatory microenvironment in CTCL and support the development of immunotherapies targeting ICOS and PD-L1 in advanced disease.