TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae.

Mohammad AlfatahJin Huei WongVidhya Gomathi KrishnanYong Cheow LeeQuan Feng SinCorinna Jie Hui GohKiat Whye KongWei Ting LeeJacqueline LewisShawn HoonPrakash Arumugam

Published in: BMC biology (2021)

Our studies indicate that a regulatory loop that involves activation of TORC1 by glucose and regulation of glucose-responsive genes by TORC1, mediates nutritional control of growth and development in yeast.

Keyphrases

saccharomyces cerevisiae
blood glucose
transcription factor
gene expression
genome wide
blood pressure
drug delivery
cancer therapy
genome wide identification